Thymosin Alpha-1 Research Peptide, US-Made & Third-Party Tested
✓ US-made · third-party tested · free US shipping over $100
last updated · reviewed by the verve research team
what is thymosin alpha-1?
Thymosin Alpha-1 is a synthetic 28-amino-acid peptide based on a sequence characterized in thymic tissue. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use. It is catalogued under longevity & cellular as a synthetic 28-amino-acid thymic peptide.
Thymosin Alpha-1 is a 28-amino-acid peptide corresponding to a sequence originally characterized in thymic tissue extracts, where it was identified as part of the prothymosin alpha precursor. Verve supplies it as a high-purity synthetic research compound for the laboratory study of peptide-mediated immunological signaling.
In research settings, Thymosin Alpha-1 is used as a reference peptide in Toll-like receptor signaling studies and in T-cell differentiation and maturation models, where investigators characterize cytokine-expression profiles in cultured cells. Verve's Thymosin Alpha-1 is manufactured in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a published batch-level certificate of analysis.
thymosin alpha-1 specifications
Reference data for Thymosin Alpha-1 as supplied by verve for laboratory research use only.
| Compound | Thymosin Alpha-1 |
|---|---|
| Compound class | Synthetic 28-amino-acid thymic peptide |
| Research area | longevity & cellular |
| Primary research focus | immunological-signaling research |
| Purity standard | 99%+ purity standard, HPLC-verified per batch |
| Supplied as | Single research compound |
| Endotoxin-tested option | Not offered |
| Catalog sizes | 10mg |
| Catalog price | from $93 |
| Availability | Out of stock |
| Intended use | In-vitro laboratory research use only. Not for human or veterinary use. |
| Reference last reviewed |
what is thymosin alpha-1 used for in research?
Thymosin Alpha-1 is supplied strictly for laboratory research use only. Reported research contexts include:
- T-cell differentiation and maturation research models
- Toll-like receptor signaling research
- Cytokine-expression profiling in cell culture
- Thymic-peptide and immunological-signaling research
- Peptide structure–activity and stability research
how pure is thymosin alpha-1?
purity, third-party testing & the certificate of analysis
Every batch of verve Thymosin Alpha-1is synthesized and vial-filled in the United States and screened by an independent, accredited laboratory. Chromatographic purity and quantity are measured by HPLC-UV/VIS; where the panel includes them, endotoxin is screened by LAL and sterility by USP <71>, with the sterility result reported as no growth detected or as pending while the culture is still running. Products are manufactured to a 99%+ purity standard where stated.
Published certificates for the lots currently in our COA library cover part of the range; a published report for this compound is not in the library yet. Orders placed Monday–Friday ship by 2pm CT, free over $100, with damage protection in transit and full US tracking.
Thymosin Alpha-1, explained in 60 secondsthe plain-english version — what it is, where it shows up, and the lab report behind the vialthymosin alpha-1 frequently asked questions
What is Thymosin Alpha-1?
Thymosin Alpha-1 is a synthetic 28-amino-acid peptide based on a sequence characterized in thymic tissue. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Thymosin Alpha-1 studied for in research?
It is used as a reference compound in immunological-signaling research, including T-cell differentiation models, Toll-like receptor pathway studies, and cytokine-expression profiling in cultured cells. Verve makes no health claims.
How pure is Verve's Thymosin Alpha-1?
It is US-made, verified to a 99%+ purity standard by HPLC, and third-party tested, with a batch COA on every order.
Is a COA included?
Yes, a downloadable certificate of analysis ships with every order and is matched to your vial's batch code.
thymosin alpha-1 research references
- Wei YT, Wang XR, Yan C, Huang F, Zhang Y, Liu X, et al. Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis. Cancer Res. 2022;82(10):1991-2002.Examined macrophage polarisation states during efferocytosis in cell-culture and murine tumour models.
- Giacomini E, Severa M, Cruciani M, Etna MP, Rizzo F, Pardini M, et al. Dual effect of Thymosin α 1 on human monocyte-derived dendritic cell in vitro stimulated with viral and bacterial toll-like receptor agonists. Expert Opin Biol Ther. 2015;15 Suppl 1:S59-70.Profiled cytokine and maturation responses of human monocyte-derived dendritic cells in vitro under TLR-agonist stimulation.
- Bozza S, Gaziano R, Bonifazi P, Zelante T, Pitzurra L, Montagnoli C, et al. Thymosin alpha1 activates the TLR9/MyD88/IRF7-dependent murine cytomegalovirus sensing for induction of anti-viral responses in vivo. Int Immunol. 2007;19(11):1261-70.Characterised TLR9/MyD88/IRF7 pathway signalling in a murine cytomegalovirus model.
- Romani L, Bistoni F, Gaziano R, Bozza S, Montagnoli C, Perruccio K, et al. Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through toll-like receptor signaling. Blood. 2004;103(11):4232-9.Examined Toll-like-receptor-dependent dendritic-cell activation and Th1 polarisation in murine and in-vitro antifungal models.
research areas thymosin alpha-1 appears in
thymosin alpha-1 vs other research compounds
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US-made, third-party tested research peptides, every vial batch-traceable, every COA one click away.
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.