IGF-1 LR3 vs Thymosin Alpha-1
IGF-1 LR3 and Thymosin Alpha-1 are both studied in longevity research, but they are different classes of compound with different reported research applications.
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Last updated August 25, 2026
How do IGF-1 LR3 and Thymosin Alpha-1 differ?
IGF-1 LR3 (Recombinant IGF-1 analog polypeptide) is catalogued under longevity & cellular research; Thymosin Alpha-1 (Synthetic 28-amino-acid thymic peptide) is catalogued under longevity & cellular research. Verve lists 5 reported research applications for IGF-1 LR3 and 5 for Thymosin Alpha-1. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | IGF-1 LR3 | Thymosin Alpha-1 |
|---|---|---|
| compound class | Recombinant IGF-1 analog polypeptide | Synthetic 28-amino-acid thymic peptide |
| research area | longevity & cellular | longevity & cellular |
| reported research applications | 5 listed | 5 listed |
| supplied as | single compound | single compound |
| catalog sizes | 1mg · 2x 1mg | 10mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | available | not offered |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $93.49 | $93.49 |
| availability | out of stock | out of stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is IGF-1 LR3 and what is Thymosin Alpha-1?
IGF-1 LR3 is classified as Recombinant IGF-1 analog polypeptide; Thymosin Alpha-1 as Synthetic 28-amino-acid thymic peptide. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
IGF-1 LR3
Recombinant IGF-1 analog polypeptide
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Those two modifications are what define it: they substantially reduce its affinity for the insulin-like growth factor binding proteins (IGFBPs) that sequester native IGF-1 in culture systems.
full IGF-1 LR3 profile →Thymosin Alpha-1
Synthetic 28-amino-acid thymic peptide
Thymosin Alpha-1 is a 28-amino-acid peptide corresponding to a sequence originally characterized in thymic tissue extracts, where it was identified as part of the prothymosin alpha precursor. Verve supplies it as a high-purity synthetic research compound for the laboratory study of peptide-mediated immunological signaling.
full Thymosin Alpha-1 profile →Which research models is each compound studied in?
IGF-1 LR3 and Thymosin Alpha-1 both sit inside longevity & cellular research, so their listed models share framing while differing in specifics. The table lists 5 reported research applications for IGF-1 LR3 and 5 for Thymosin Alpha-1. Rows are per compound, not equivalences.
| IGF-1 LR3 — reported research applications | Thymosin Alpha-1 — reported research applications |
|---|---|
| IGF-1 receptor binding and signal-transduction research | T-cell differentiation and maturation research models |
| PI3K/Akt and MAPK pathway research in cellular models | Toll-like receptor signaling research |
| Cell-culture media supplementation for proliferation research | Cytokine-expression profiling in cell culture |
| IGFBP interaction and free-ligand availability studies | Thymic-peptide and immunological-signaling research |
| Comparative analog research against native IGF-1 | Peptide structure–activity and stability research |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for IGF-1 LR3 and Thymosin Alpha-1?
IGF-1 LR3 is listed from $93.49 and Thymosin Alpha-1 from $93.49. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| IGF-1 LR3 | 1mg | $93.49 | out of stock |
| IGF-1 LR3 | 2x 1mg | $171.49 | out of stock |
| Thymosin Alpha-1 | 10mg | $93.49 | out of stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about IGF-1 LR3 and Thymosin Alpha-1
What is IGF-1 LR3?
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 with an arginine substitution at position 3 and an N-terminal extension. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
How does IGF-1 LR3 differ from native IGF-1?
Its structural modifications reduce affinity for IGF binding proteins, so more of the ligand remains unbound in culture systems. Researchers use that property to control free-ligand availability in in-vitro models.
What is Thymosin Alpha-1?
Thymosin Alpha-1 is a synthetic 28-amino-acid peptide based on a sequence characterized in thymic tissue. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Thymosin Alpha-1 studied for in research?
It is used as a reference compound in immunological-signaling research, including T-cell differentiation models, Toll-like receptor pathway studies, and cytokine-expression profiling in cultured cells. Verve makes no health claims.
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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.