CJC-1295 / Ipamorelin vs IGF-1 LR3
CJC-1295 / Ipamorelin and IGF-1 LR3 are both studied in longevity research, but they are different classes of compound with different reported research applications.
✓ both US-made · third-party tested · batch COA on every order
Last updated August 25, 2026
How do CJC-1295 / Ipamorelin and IGF-1 LR3 differ?
CJC-1295 / Ipamorelin (Co-formulated GHRH-analog and secretagogue blend) is catalogued under longevity & cellular research; IGF-1 LR3 (Recombinant IGF-1 analog polypeptide) is catalogued under longevity & cellular research. Verve lists 5 reported research applications for CJC-1295 / Ipamorelin and 5 for IGF-1 LR3. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | CJC-1295 / Ipamorelin | IGF-1 LR3 |
|---|---|---|
| compound class | Co-formulated GHRH-analog and secretagogue blend | Recombinant IGF-1 analog polypeptide |
| research area | longevity & cellular | longevity & cellular |
| reported research applications | 5 listed | 5 listed |
| supplied as | co-formulated blend | single compound |
| catalog sizes | 10mg | 1mg · 2x 1mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | available | available |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $157.49 | $93.49 |
| availability | in stock | out of stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is CJC-1295 / Ipamorelin and what is IGF-1 LR3?
CJC-1295 / Ipamorelin is classified as Co-formulated GHRH-analog and secretagogue blend; IGF-1 LR3 as Recombinant IGF-1 analog polypeptide. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
CJC-1295 / Ipamorelin
Co-formulated GHRH-analog and secretagogue blend
CJC-1295 / Ipamorelin is a co-formulated research blend of two peptides that act at separate receptors. CJC-1295 without DAC, also referred to as Mod GRF 1-29, is a modified 29-amino-acid analog of growth-hormone-releasing hormone characterized as a GHRH-receptor agonist. Ipamorelin is a synthetic pentapeptide characterized as a selective agonist at the growth-hormone secretagogue receptor, GHS-R1a.
full CJC-1295 / Ipamorelin profile →IGF-1 LR3
Recombinant IGF-1 analog polypeptide
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Those two modifications are what define it: they substantially reduce its affinity for the insulin-like growth factor binding proteins (IGFBPs) that sequester native IGF-1 in culture systems.
full IGF-1 LR3 profile →Which research models is each compound studied in?
CJC-1295 / Ipamorelin and IGF-1 LR3 both sit inside longevity & cellular research, so their listed models share framing while differing in specifics. The table lists 5 reported research applications for CJC-1295 / Ipamorelin and 5 for IGF-1 LR3. Rows are per compound, not equivalences.
| CJC-1295 / Ipamorelin — reported research applications | IGF-1 LR3 — reported research applications |
|---|---|
| Dual-pathway GHRH-receptor and GHS-R1a signaling research | IGF-1 receptor binding and signal-transduction research |
| Receptor cross-talk and signal-transduction research models | PI3K/Akt and MAPK pathway research in cellular models |
| Comparative agonist research versus single-component preparations | Cell-culture media supplementation for proliferation research |
| Endocrine-signaling research in cellular and pre-clinical models | IGFBP interaction and free-ligand availability studies |
| Peptide stability and analog structure–activity research | Comparative analog research against native IGF-1 |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for CJC-1295 / Ipamorelin and IGF-1 LR3?
CJC-1295 / Ipamorelin is listed from $157.49 and IGF-1 LR3 from $93.49. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| CJC-1295 / Ipamorelin | 10mg | $157.49 | in stock |
| IGF-1 LR3 | 1mg | $93.49 | out of stock |
| IGF-1 LR3 | 2x 1mg | $171.49 | out of stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about CJC-1295 / Ipamorelin and IGF-1 LR3
What is CJC-1295 / Ipamorelin?
It is a co-formulated research blend of CJC-1295 without DAC (also called Mod GRF 1-29), a GHRH analog, and ipamorelin, a selective GHS-R1a agonist. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is the difference between CJC-1295 with and without DAC?
The DAC (drug affinity complex) modification is a chemical addition studied for its effect on the analog's circulating half-life in pre-clinical models. The no-DAC form, Mod GRF 1-29, lacks that modification and is the component used in this blend.
What is IGF-1 LR3?
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 with an arginine substitution at position 3 and an N-terminal extension. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
How does IGF-1 LR3 differ from native IGF-1?
Its structural modifications reduce affinity for IGF binding proteins, so more of the ligand remains unbound in culture systems. Researchers use that property to control free-ligand availability in in-vitro models.
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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.