Ipamorelin Research Peptide, US-Made & Third-Party Tested
✓ US-made · third-party tested · free US shipping over $100
last updated · reviewed by the verve research team
what is ipamorelin?
Ipamorelin is a synthetic pentapeptide characterized as a selective agonist at the growth-hormone secretagogue receptor (GHS-R1a). Verve supplies it as a research compound for laboratory use only, not for human or veterinary use. It is catalogued under longevity & cellular as a synthetic pentapeptide secretagogue.
Ipamorelin is a synthetic pentapeptide and a selective growth-hormone secretagogue, meaning it is characterized in the literature as an agonist at the growth-hormone secretagogue receptor (GHS-R1a), the same receptor targeted by the endogenous ligand ghrelin. Its selectivity profile is the reason it is so frequently chosen as a reference agonist in receptor-signaling work.
In cellular and pre-clinical systems, ipamorelin is used to probe GHS-R1a binding, receptor-occupancy, and downstream signal-transduction cascades, and as a comparator against GHRH-receptor agonists that act through a separate pathway. Verve manufactures ipamorelin in the United States, screens every batch by HPLC to a 99%+ purity standard, and publishes a batch-level certificate of analysis.
ipamorelin specifications
Reference data for Ipamorelin as supplied by verve for laboratory research use only.
| Compound | Ipamorelin |
|---|---|
| Compound class | Synthetic pentapeptide secretagogue |
| Research area | longevity & cellular |
| Primary research focus | receptor-signaling research |
| Purity standard | 99%+ purity standard, HPLC-verified per batch |
| Supplied as | Single research compound |
| Endotoxin-tested option | Available |
| Catalog sizes | 5mg · 10mg |
| Catalog price | from $65 |
| Availability | Out of stock |
| Also supplied in | CJC-1295 / Ipamorelin |
| Intended use | In-vitro laboratory research use only. Not for human or veterinary use. |
| Reference last reviewed |
what is ipamorelin used for in research?
Ipamorelin is supplied strictly for laboratory research use only. Reported research contexts include:
- GHS-R1a (ghrelin receptor) binding and agonist research
- Secretagogue-pathway signal-transduction research
- Comparative receptor-selectivity studies against non-selective secretagogues
- Endocrine-signaling research models
- Peptide stability and structure–activity research
how pure is ipamorelin?
purity, third-party testing & the certificate of analysis
Every batch of verve Ipamorelinis synthesized and vial-filled in the United States and screened by an independent, accredited laboratory. Chromatographic purity and quantity are measured by HPLC-UV/VIS; where the panel includes them, endotoxin is screened by LAL and sterility by USP <71>, with the sterility result reported as no growth detected or as pending while the culture is still running. Products are manufactured to a 99%+ purity standard where stated.
That lab report is the certificate of analysis. Match the batch code printed on your vial to the row in our COA library and you're reading the exact report for the exact vial in your hand. This compound's current report covers lot 3548189, published 2026-05-27. Orders placed Monday–Friday ship by 2pm CT, free over $100, with damage protection in transit and full US tracking.
Ipamorelin, explained in 60 secondsthe plain-english version — what it is, where it shows up, and the lab report behind the vialipamorelin frequently asked questions
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide characterized as a selective agonist at the growth-hormone secretagogue receptor (GHS-R1a). Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Ipamorelin studied for in research?
It is used as a reference agonist in GHS-R1a receptor-binding and secretagogue-pathway signaling research in in-vitro and pre-clinical models. Verve makes no claims about effects in humans or animals.
What does "selective secretagogue" mean in this context?
It refers to the receptor-binding profile reported in the literature: ipamorelin is characterized as acting at GHS-R1a with limited activity at related receptors, which makes it useful for isolating that pathway in laboratory models.
How pure is Verve's Ipamorelin, and is a COA included?
It is US-made, verified to a 99%+ purity standard by HPLC on every batch, and shipped with a downloadable batch-level certificate of analysis matched to your vial's batch code.
ipamorelin research references
- Venkova K, Mann W, Nelson R, Greenwood-Van Meerveld B. Efficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileus. J Pharmacol Exp Ther. 2009;329(3):1110-6.Characterised gastrointestinal transit endpoints of a ghrelin-receptor mimetic in a rodent postoperative-ileus model.
- Andersen NB, Malmlöf K, Johansen PB, Andreassen TT, Ørtoft G, Oxlund H. The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats. Growth Horm IGF Res. 2001;11(5):266-72.Examined bone-formation markers in a glucocorticoid-challenged adult rat model.
- Svensson J, Lall S, Dickson SL, Bengtsson BA, Rømer J, Ahnfelt-Rønne I, et al. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats. J Endocrinol. 2000;165(3):569-77.Comparative study of two secretagogues against bone-mineral-content endpoints in adult female rats.
- Johansen PB, Nowak J, Skjaerbaek C, Flyvbjerg A, Andreassen TT, Wilken M, et al. Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats. Growth Horm IGF Res. 1999;9(2):106-13.Measured longitudinal bone-growth endpoints in a rat model.
- Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-61.Original characterisation of the pentapeptide, reporting its receptor-selectivity profile in in-vitro pituitary systems and rat models.
research areas ipamorelin appears in
ipamorelin vs other research compounds
all comparisons →research compounds related to ipamorelin
purity, proven.
US-made, third-party tested research peptides, every vial batch-traceable, every COA one click away.
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.