NAD+ and cellular redox research
Reference library · last updated · research use only
What is NAD+ and cellular redox research?
Redox research characterizes the oxidation state of a cellular system, most often through the NAD+/NADH ratio and the glutathione / glutathione-disulfide couple. Those two measurements underpin a large share of the cellular energy-metabolism and oxidative-stress literature, and both are made in cultured cell systems.
Redox research characterizes the oxidation state of a cellular system, most often through the NAD+/NADH ratio and the glutathione / glutathione-disulfide couple. Those two measurements underpin a large share of cellular energy-metabolism and oxidative-stress literature.
The compounds below are the reference molecules used to manipulate and measure those systems in the laboratory. Each is research-use-only, US-made, and supplied with a batch-level certificate of analysis.
What is measured in NAD+ and cellular redox research?
NAD+ and cellular redox research is characterized in the laboratory through NAD+/NADH ratio, glutathione / glutathione-disulfide (GSH/GSSG) couple and salvage-pathway models. These are the endpoints recorded in the model itself; Verve makes no claim about what any compound does in a person or an animal.
- NAD+/NADH ratio
- Glutathione / glutathione-disulfide (GSH/GSSG) couple
- Salvage-pathway models
Which compounds are studied in NAD+ and cellular redox research?
Verve lists 4 reference compounds in NAD+ and cellular redox research: NAD+, Glutathione, 5-Amino-1MQ and MOTS-C. Each is manufactured in the United States, screened by an independent laboratory, and supplied strictly for in-vitro research with a batch-level certificate of analysis.
| Compound | Classification | Also studied in |
|---|---|---|
| NAD+ | Nicotinamide adenine dinucleotide · cellular-metabolism research | mitochondrial-function, cellular-senescence |
| Glutathione | Redox-active tripeptide · cellular redox research | mitochondrial-function, cellular-senescence |
| 5-Amino-1MQ | Small-molecule enzyme inhibitor (not a peptide) | metabolic-pathway, mitochondrial-function |
| MOTS-C | Mitochondrial-derived 16-amino-acid peptide | metabolic-pathway, mitochondrial-function |
Compare compounds within NAD+ and cellular redox research
These side-by-side references compare two compounds that both appear in NAD+ and cellular redox research, on scientific identity, classification, and the models each one is cited in. All compounds compared are supplied for laboratory research use only.
NAD+ and cellular redox research, frequently asked
What is the NAD+/NADH ratio used for in research?
The NAD+/NADH ratio is one of the measurements researchers use to characterize the oxidation state of a cellular system. Together with the glutathione / glutathione-disulfide couple it underpins a large share of the cellular energy-metabolism and oxidative-stress literature.
Which compounds are used in cellular redox research?
NAD+, glutathione and NNMT inhibitors are the reference molecules used to manipulate and measure cellular redox systems in the laboratory. Verve supplies each as a research-use-only preparation with a batch-level certificate of analysis.
Are Verve's research compounds available for human or veterinary use?
No. Every compound Verve lists is supplied strictly as a reference material for in-vitro laboratory research. Nothing on this site is a drug, a supplement, or a treatment, and no statement describes what a compound does in a person or an animal.
How is the material behind a research result documented?
Every lot is manufactured in the United States, screened by an independent laboratory, and published with a batch-level certificate of analysis. Matching the batch code printed on the vial to the row in Verve's COA library gives the report for that exact lot.
Related research areas
Reference compounds are routinely cited across several laboratory models, so the areas below overlap with NAD+ and cellular redox research in the compounds they list. Each links to its own page stating what that model examines and what is measured in it.
Tissue-repair research peptides
Cell migration, wound-healing and connective-tissue modelsExtracellular-matrix and remodeling research
Matrix remodeling, collagen expression and structural protein modelsDermal and collagen research peptides
Fibroblast, collagen-expression and dermal cell-culture modelsMetabolic-pathway research peptides
Incretin receptors, amylin signaling and nutrient-handling modelsMitochondrial-function research compounds
Mitochondrial-derived peptides, AMPK signaling and energy metabolismCellular-senescence and replicative-aging research
Telomerase expression, replicative aging and senescence modelspurity, proven.
US-made, third-party tested research compounds. Every vial batch-traceable, every COA one click away.
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