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Glutathione vs MOTS-C

Glutathione and MOTS-C come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.

✓ both US-made · third-party tested · batch COA on every order

Last updated August 25, 2026

How do Glutathione and MOTS-C differ?

Glutathione (Redox-active tripeptide · cellular redox research) is catalogued under longevity & cellular research; MOTS-C (Mitochondrial-derived 16-amino-acid peptide) is catalogued under weight & metabolic research. Verve lists 4 reported research applications for Glutathione and 5 for MOTS-C. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.

Glutathione compared with MOTS-C across compound class, research area, supply format, purity standard, documentation, catalog price and stock.
fieldGlutathioneMOTS-C
compound classRedox-active tripeptide · cellular redox researchMitochondrial-derived 16-amino-acid peptide
research arealongevity & cellularweight & metabolic
reported research applications4 listed5 listed
supplied assingle compoundsingle compound
catalog sizes1500mg10mg
purity standard99%+ by HPLC99%+ by HPLC
manufacturedUnited StatesUnited States
batch COApublished per lotpublished per lot
endotoxin-tested optionnot offeredavailable
co-formulated together innot co-formulatednot co-formulated
price from$142.99$78.99
availabilityin stockin stock

Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.

What is Glutathione and what is MOTS-C?

Glutathione is classified as Redox-active tripeptide · cellular redox research; MOTS-C as Mitochondrial-derived 16-amino-acid peptide. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.

Glutathione

Redox-active tripeptide · cellular redox research

Glutathione is a tripeptide composed of glutamate, cysteine, and glycine (γ-glutamylcysteinylglycine) and the principal redox-active thiol found inside the cell. Verve supplies a high-purity research preparation for the study of cellular redox chemistry.

full Glutathione profile →

MOTS-C

Mitochondrial-derived 16-amino-acid peptide

MOTS-c is a 16-amino-acid peptide encoded not by nuclear DNA but by a short open reading frame within the mitochondrial 12S rRNA gene. It belongs to the mitochondrial-derived peptide family, a group of small peptides that are of interest in research precisely because their genetic origin sits inside the organelle rather than the nucleus.

full MOTS-C profile →

Which research models is each compound studied in?

Glutathione sits in longevity & cellular research and MOTS-C in weight & metabolic research, so their listed models largely do not intersect. The table lists 4 reported research applications for Glutathione and 5 for MOTS-C. Rows are per compound, not equivalences.

Reported research applications listed for Glutathione and for MOTS-C. Entries are listed per compound; a shared row is not a claim that the two applications are equivalent.
Glutathione — reported research applicationsMOTS-C — reported research applications
Oxidative-stress research modelsMitochondrial-derived peptide and retrograde-signaling research
Cellular redox (GSH/GSSG) researchAMPK pathway research models
Detoxification-pathway studiesOne-carbon (folate–methionine) metabolism studies
Thiol- and antioxidant-chemistry researchCellular energy-metabolism and substrate-utilization research
Exercise-physiology and metabolic-stress research models

Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.

What sizes and prices does verve list for Glutathione and MOTS-C?

Glutathione is listed from $142.99 and MOTS-C from $78.99. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.

Catalog sizes, single-vial prices and stock status for Glutathione and MOTS-C.
compoundsize listedpriceavailability
Glutathione1500mg$142.99in stock
MOTS-C10mg$78.99in stock

Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.

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Frequently asked questions about Glutathione and MOTS-C

What is glutathione?

Glutathione is a tripeptide (glutamate–cysteine–glycine) and the cell's principal redox-active thiol. Verve supplies it as a research compound for laboratory use only.

What is glutathione studied for in research?

It is used in oxidative-stress, cellular-redox, and detoxification-pathway research. Verve makes no human- or veterinary-use claims.

What is MOTS-C?

MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame in the mitochondrial genome. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.

What is MOTS-C studied for in research?

It is used in mitochondrial-signaling research, including AMPK pathway activity, one-carbon metabolism, and retrograde signaling between mitochondria and the nucleus in in-vitro and pre-clinical models. Verve makes no health claims.

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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.