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thymosin β4 fragment · tissue-repair research

TB-500 Research Peptide, US-Made & Third-Party Tested

✓ US-made · third-party tested · free US shipping over $100

last updated · reviewed by the verve research team

what is tb-500?

TB-500 is a synthetic 43-amino-acid peptide based on an active fragment of thymosin beta-4. Verve supplies it as a research compound for laboratory use only. It is catalogued under recovery & gut as a thymosin β4 fragment. Every batch is US-made, third-party tested, and shipped with batch-level documentation.

TB-500 is a synthetic 43-amino-acid peptide corresponding to an active fragment of thymosin beta-4, a naturally-occurring actin-binding protein. Verve supplies it as a high-purity research compound for tissue-repair and cellular research.

TB-500 is studied for its role in models of cell migration, actin regulation, and angiogenesis, the cytoskeletal and repair processes associated with thymosin beta-4. Verve's TB-500 is US-made, third-party tested, and batch-traceable via its published COA.

tb-500 specifications

Reference data for TB-500 as supplied by verve for laboratory research use only.

TB-500 research compound specifications
CompoundTB-500
Compound classThymosin β4 fragment
Research arearecovery & gut
Primary research focustissue-repair research
Purity standard99%+ purity standard, HPLC-verified per batch
Supplied asSingle research compound
Endotoxin-tested optionAvailable
Catalog sizes10mg
Catalog pricefrom $93
AvailabilityIn stock
Also supplied inKLOW · BPC-157 + TB-500 · GLOW
Intended useIn-vitro laboratory research use only. Not for human or veterinary use.
Reference last reviewed

what is tb-500 used for in research?

TB-500 is supplied strictly for laboratory research use only. Reported research contexts include:

  • Cell-migration research models
  • Actin-regulation and cytoskeletal research
  • Angiogenesis research
  • Tissue-repair research models

how pure is tb-500?

purity, third-party testing & the certificate of analysis

Every batch of verve TB-500is synthesized and vial-filled in the United States and screened by an independent, accredited laboratory. Chromatographic purity and quantity are measured by HPLC-UV/VIS; where the panel includes them, endotoxin is screened by LAL and sterility by USP <71>, with the sterility result reported as no growth detected or as pending while the culture is still running. Products are manufactured to a 99%+ purity standard where stated.

Published certificates for the lots currently in our COA library cover part of the range; a published report for this compound is not in the library yet. Orders placed Monday–Friday ship by 2pm CT, free over $100, with damage protection in transit and full US tracking.

TB-500, explained in 60 secondsthe plain-english version — what it is, where it shows up, and the lab report behind the vial

where to buy tb-500 for research

TB-500TB-500recovery & gutfrom $93browse all recovery & gut

tb-500 frequently asked questions

What is TB-500?

TB-500 is a synthetic 43-amino-acid peptide based on an active fragment of thymosin beta-4. Verve supplies it as a research compound for laboratory use only.

What is TB-500 studied for in research?

It is used in cell-migration, actin-regulation, angiogenesis, and tissue-repair research models. It is not for human or veterinary use.

How pure is Verve's TB-500?

It is US-made, verified to a 99%+ purity standard by HPLC, and third-party tested, with a batch COA and an endotoxin-tested option available.

Is a COA included?

Yes, every order ships with a downloadable batch-level certificate of analysis.

tb-500 research references

  1. Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. 2004;432(7016):466-72.Thymosin beta-4 study: characterised binding to the PINCH/integrin-linked kinase complex and cell migration and survival in murine cardiac models.
  2. Sosne G, Szliter EA, Barrett R, Kernacki KA, Kleinman H, Hazlett LD. Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury. Exp Eye Res. 2002;74(2):293-9.Thymosin beta-4 study: assessed epithelial repair and inflammatory-cell infiltration in a mouse corneal alkali-injury model.
  3. De La Cruz EM, Ostap EM, Brundage RA, Reddy KS, Sweeney HL, Safer D. Thymosin-beta(4) changes the conformation and dynamics of actin monomers. Biophys J. 2000;78(5):2516-27.Thymosin beta-4 study: characterised the biophysics of binding to G-actin monomers and the resulting conformational changes in vitro.
  4. Malinda KM, Sidhu GS, Mani H, Banaudha K, Maheshwari RK, Goldstein AL, et al. Thymosin beta4 accelerates wound healing. J Invest Dermatol. 1999;113(3):364-8.Thymosin beta-4 study: examined keratinocyte migration, collagen deposition, and angiogenesis endpoints in a rodent full-thickness dermal wound model.
  5. Malinda KM, Goldstein AL, Kleinman HK. Thymosin beta 4 stimulates directional migration of human umbilical vein endothelial cells. FASEB J. 1997;11(6):474-81.Thymosin beta-4 study: measured directional migration of cultured endothelial cells in an in-vitro chemotaxis assay.

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US-made, third-party tested research peptides, every vial batch-traceable, every COA one click away.

verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.