Epitalon vs TB-500
Epitalon and TB-500 come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.
✓ both US-made · third-party tested · batch COA on every order
Last updated August 25, 2026
How do Epitalon and TB-500 differ?
Epitalon (Synthetic tetrapeptide) is catalogued under longevity & cellular research; TB-500 (Thymosin β4 fragment · tissue-repair research) is catalogued under recovery & gut research. Verve lists 5 reported research applications for Epitalon and 4 for TB-500. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | Epitalon | TB-500 |
|---|---|---|
| compound class | Synthetic tetrapeptide | Thymosin β4 fragment · tissue-repair research |
| research area | longevity & cellular | recovery & gut |
| reported research applications | 5 listed | 4 listed |
| supplied as | single compound | single compound |
| catalog sizes | 10mg · 50mg | 10mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | not offered | available |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $50.49 | $93.49 |
| availability | out of stock | in stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is Epitalon and what is TB-500?
Epitalon is classified as Synthetic tetrapeptide; TB-500 as Thymosin β4 fragment · tissue-repair research. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
Epitalon
Synthetic tetrapeptide
Epitalon is a synthetic tetrapeptide with the sequence alanyl-glutamyl-aspartyl-glycine (Ala-Glu-Asp-Gly), developed as a short synthetic analog of a peptide fraction isolated from the pineal gland. It is a small, water-soluble peptide and one of the most frequently cited reference compounds in pineal-peptide and cellular-aging research literature.
full Epitalon profile →TB-500
Thymosin β4 fragment · tissue-repair research
TB-500 is a synthetic 43-amino-acid peptide corresponding to an active fragment of thymosin beta-4, a naturally-occurring actin-binding protein. Verve supplies it as a high-purity research compound for tissue-repair and cellular research.
full TB-500 profile →Which research models is each compound studied in?
Epitalon sits in longevity & cellular research and TB-500 in recovery & gut research, so their listed models largely do not intersect. The table lists 5 reported research applications for Epitalon and 4 for TB-500. Rows are per compound, not equivalences.
| Epitalon — reported research applications | TB-500 — reported research applications |
|---|---|
| Telomerase-expression research models | Cell-migration research models |
| Pineal-peptide and circadian-signaling research | Actin-regulation and cytoskeletal research |
| Chromatin and gene-regulation studies | Angiogenesis research |
| Cellular-senescence and replicative-aging research models | Tissue-repair research models |
| Short-peptide stability and synthesis research | — |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for Epitalon and TB-500?
Epitalon is listed from $50.49 and TB-500 from $93.49. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| Epitalon | 10mg | $50.49 | out of stock |
| Epitalon | 50mg | $64.99 | out of stock |
| TB-500 | 10mg | $93.49 | in stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about Epitalon and TB-500
What is Epitalon?
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on a peptide fraction identified in the pineal gland. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Epitalon studied for in research?
In in-vitro and pre-clinical research it is used as a reference compound in telomerase-expression, gene-regulation, cellular-senescence, and pineal-peptide signaling models. Verve makes no claims about use in humans or animals.
What is TB-500?
TB-500 is a synthetic 43-amino-acid peptide based on an active fragment of thymosin beta-4. Verve supplies it as a research compound for laboratory use only.
What is TB-500 studied for in research?
It is used in cell-migration, actin-regulation, angiogenesis, and tissue-repair research models. It is not for human or veterinary use.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.