IGF-1 LR3 vs NAD+
IGF-1 LR3 and NAD+ are both studied in longevity research, but they are different classes of compound with different reported research applications.
✓ both US-made · third-party tested · batch COA on every order
Last updated August 25, 2026
How do IGF-1 LR3 and NAD+ differ?
IGF-1 LR3 (Recombinant IGF-1 analog polypeptide) is catalogued under longevity & cellular research; NAD+ (Nicotinamide adenine dinucleotide · cellular-metabolism research) is catalogued under longevity & cellular research. Verve lists 5 reported research applications for IGF-1 LR3 and 5 for NAD+. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | IGF-1 LR3 | NAD+ |
|---|---|---|
| compound class | Recombinant IGF-1 analog polypeptide | Nicotinamide adenine dinucleotide · cellular-metabolism research |
| research area | longevity & cellular | longevity & cellular |
| reported research applications | 5 listed | 5 listed |
| supplied as | single compound | single compound |
| catalog sizes | 1mg · 2x 1mg | 1000mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | available | available |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $93.49 | $78.99 |
| availability | out of stock | in stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is IGF-1 LR3 and what is NAD+?
IGF-1 LR3 is classified as Recombinant IGF-1 analog polypeptide; NAD+ as Nicotinamide adenine dinucleotide · cellular-metabolism research. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
IGF-1 LR3
Recombinant IGF-1 analog polypeptide
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Those two modifications are what define it: they substantially reduce its affinity for the insulin-like growth factor binding proteins (IGFBPs) that sequester native IGF-1 in culture systems.
full IGF-1 LR3 profile →NAD+
Nicotinamide adenine dinucleotide · cellular-metabolism research
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell and central to redox reactions and cellular energy metabolism. Verve's NAD+ is a high-purity research preparation supplied for the laboratory study of cellular energetics and redox biology.
full NAD+ profile →Which research models is each compound studied in?
IGF-1 LR3 and NAD+ both sit inside longevity & cellular research, so their listed models share framing while differing in specifics. The table lists 5 reported research applications for IGF-1 LR3 and 5 for NAD+. Rows are per compound, not equivalences.
| IGF-1 LR3 — reported research applications | NAD+ — reported research applications |
|---|---|
| IGF-1 receptor binding and signal-transduction research | Cellular energy-metabolism research |
| PI3K/Akt and MAPK pathway research in cellular models | Sirtuin and PARP enzyme research |
| Cell-culture media supplementation for proliferation research | Mitochondrial-function research models |
| IGFBP interaction and free-ligand availability studies | Redox-biology (NAD+/NADH ratio) research |
| Comparative analog research against native IGF-1 | Longevity and cellular-aging research models |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for IGF-1 LR3 and NAD+?
IGF-1 LR3 is listed from $93.49 and NAD+ from $78.99. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| IGF-1 LR3 | 1mg | $93.49 | out of stock |
| IGF-1 LR3 | 2x 1mg | $171.49 | out of stock |
| NAD+ | 1000mg | $78.99 | in stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about IGF-1 LR3 and NAD+
What is IGF-1 LR3?
IGF-1 LR3 is Long R3 insulin-like growth factor 1, a recombinant analog of human IGF-1 with an arginine substitution at position 3 and an N-terminal extension. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
How does IGF-1 LR3 differ from native IGF-1?
Its structural modifications reduce affinity for IGF binding proteins, so more of the ligand remains unbound in culture systems. Researchers use that property to control free-ligand availability in in-vitro models.
What is NAD+?
NAD+ is nicotinamide adenine dinucleotide, a coenzyme central to redox reactions and energy metabolism in cells. Verve supplies a high-purity research preparation for laboratory use only.
What is NAD+ studied for in research?
It is used in research on cellular energy metabolism, sirtuin and PARP enzyme activity, mitochondrial function, and DNA-repair pathways. It is not for human or veterinary use.
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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.