AOD-9604 Research Peptide, US-Made & Third-Party Tested
✓ US-made · third-party tested · free US shipping over $100
last updated · reviewed by the verve research team
what is aod-9604?
AOD-9604 is a synthetic peptide based on the 176–191 C-terminal fragment of human growth hormone, with an added N-terminal tyrosine. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use. It is catalogued under weight & metabolic as a modified human growth hormone fragment.
AOD-9604 is a synthetic peptide corresponding to the C-terminal 176–191 fragment of human growth hormone, modified by the addition of a tyrosine residue at the N-terminus to improve stability. Unlike the full-length hormone, the fragment lacks the regions associated with growth-hormone receptor binding, which is what makes it useful as a dissociated structural probe in research.
In vitro and in pre-clinical models, AOD-9604 is studied as a reference compound in lipid-metabolism research, including adipocyte signaling, lipolytic and lipogenic enzyme pathways, and structure–activity work comparing the fragment against full-length growth hormone. Verve manufactures AOD-9604 in the United States, screens every batch by HPLC to a 99%+ purity standard, and publishes a batch-level certificate of analysis.
aod-9604 specifications
Reference data for AOD-9604 as supplied by verve for laboratory research use only.
| Compound | AOD-9604 |
|---|---|
| Compound class | Modified human growth hormone fragment |
| Research area | weight & metabolic |
| Primary research focus | lipid-metabolism research |
| Purity standard | 99%+ purity standard, HPLC-verified per batch |
| Supplied as | Single research compound |
| Endotoxin-tested option | Not offered |
| Catalog sizes | 10mg |
| Catalog price | from $114 |
| Availability | Out of stock |
| Intended use | In-vitro laboratory research use only. Not for human or veterinary use. |
| Reference last reviewed |
what is aod-9604 used for in research?
AOD-9604 is supplied strictly for laboratory research use only. Reported research contexts include:
- Lipid-metabolism and adipocyte-signaling research models
- Growth-hormone fragment structure–activity research
- Lipolytic and lipogenic enzyme pathway studies
- Comparative studies against full-length growth hormone
- Body-composition research endpoints in pre-clinical models
how pure is aod-9604?
purity, third-party testing & the certificate of analysis
Every batch of verve AOD-9604is synthesized and vial-filled in the United States and screened by an independent, accredited laboratory. Chromatographic purity and quantity are measured by HPLC-UV/VIS; where the panel includes them, endotoxin is screened by LAL and sterility by USP <71>, with the sterility result reported as no growth detected or as pending while the culture is still running. Products are manufactured to a 99%+ purity standard where stated.
Published certificates for the lots currently in our COA library cover part of the range; a published report for this compound is not in the library yet. Orders placed Monday–Friday ship by 2pm CT, free over $100, with damage protection in transit and full US tracking.
AOD-9604, explained in 60 secondsthe plain-english version — what it is, where it shows up, and the lab report behind the vialaod-9604 frequently asked questions
What is AOD-9604?
AOD-9604 is a synthetic peptide based on the 176–191 C-terminal fragment of human growth hormone, with an added N-terminal tyrosine. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is AOD-9604 studied for in research?
It is used as a reference compound in lipid-metabolism, adipocyte-signaling, and enzyme-pathway research, and in structure–activity studies comparing fragments to full-length growth hormone. Verve makes no claims about use in humans or animals.
How does AOD-9604 differ from full-length growth hormone?
It reproduces only the 176–191 region and lacks the domains associated with growth-hormone receptor binding, which is why researchers use it to separate fragment-specific pathway activity from whole-hormone signaling in laboratory models.
How pure is Verve's AOD-9604, and is a COA included?
It is US-made, verified by HPLC to a 99%+ purity standard, and third-party tested, with a downloadable batch-level certificate of analysis included on every order.
aod-9604 research references
- Kwon DR, Park GY. Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model. Ann Clin Lab Sci. 2015;45(4):426-32.Examined cartilage and joint-tissue histological endpoints following intra-articular administration in a rabbit osteoarthritis model.
- Cox HD, Smeal SJ, Hughes CM, Cox JE, Eichner D. Detection and in vitro metabolism of AOD9604. Drug Test Anal. 2015;7(1):31-8.Characterised the in-vitro metabolic fate and mass-spectrometric detection of the peptide fragment for analytical purposes.
- Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, et al. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology. 2001;142(12):5182-9.Examined lipolytic and lipogenic enzyme activity after chronic administration in obese mice and in beta-3 adrenergic receptor knockout mice, to test receptor dependence of the fragment.
- Heffernan MA, Thorburn AW, Fam B, Summers R, Conway-Campbell B, Waters MJ, et al. Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment. Int J Obes Relat Metab Disord. 2001;25(10):1442-9.Compared substrate-oxidation and body-composition endpoints in obese mice given full-length human growth hormone versus the modified C-terminal fragment.
research areas aod-9604 appears in
aod-9604 vs other research compounds
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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.