PT-141 vs TB-500
PT-141 and TB-500 come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.
✓ both US-made · third-party tested · batch COA on every order
Last updated August 25, 2026
How do PT-141 and TB-500 differ?
PT-141 (Synthetic cyclic heptapeptide melanocortin agonist) is catalogued under skin & glow research; TB-500 (Thymosin β4 fragment · tissue-repair research) is catalogued under recovery & gut research. Verve lists 5 reported research applications for PT-141 and 4 for TB-500. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | PT-141 | TB-500 |
|---|---|---|
| compound class | Synthetic cyclic heptapeptide melanocortin agonist | Thymosin β4 fragment · tissue-repair research |
| research area | skin & glow | recovery & gut |
| reported research applications | 5 listed | 4 listed |
| supplied as | single compound | single compound |
| catalog sizes | 10mg | 10mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | not offered | available |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $50.49 | $93.49 |
| availability | out of stock | in stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is PT-141 and what is TB-500?
PT-141 is classified as Synthetic cyclic heptapeptide melanocortin agonist; TB-500 as Thymosin β4 fragment · tissue-repair research. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
PT-141
Synthetic cyclic heptapeptide melanocortin agonist
PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide analog of the melanocortin family, structurally related to alpha-melanocyte-stimulating hormone and to the earlier research analog Melanotan II. Verve supplies it as a high-purity research compound for laboratory melanocortin-receptor research.
full PT-141 profile →TB-500
Thymosin β4 fragment · tissue-repair research
TB-500 is a synthetic 43-amino-acid peptide corresponding to an active fragment of thymosin beta-4, a naturally-occurring actin-binding protein. Verve supplies it as a high-purity research compound for tissue-repair and cellular research.
full TB-500 profile →Which research models is each compound studied in?
PT-141 sits in skin & glow research and TB-500 in recovery & gut research, so their listed models largely do not intersect. The table lists 5 reported research applications for PT-141 and 4 for TB-500. Rows are per compound, not equivalences.
| PT-141 — reported research applications | TB-500 — reported research applications |
|---|---|
| Melanocortin-receptor (MC1R/MC3R/MC4R) binding research | Cell-migration research models |
| cAMP and G-protein-coupled receptor signaling assays | Actin-regulation and cytoskeletal research |
| Receptor-selectivity and structure–activity profiling | Angiogenesis research |
| MC1R and melanogenesis research models in cell culture | Tissue-repair research models |
| Cyclic-peptide stability and conformation research | — |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for PT-141 and TB-500?
PT-141 is listed from $50.49 and TB-500 from $93.49. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| PT-141 | 10mg | $50.49 | out of stock |
| TB-500 | 10mg | $93.49 | in stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about PT-141 and TB-500
What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide melanocortin analog structurally related to alpha-MSH. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is PT-141 studied for in research?
It is used as a reference agonist in melanocortin-receptor research, including MC1R, MC3R, and MC4R binding studies, cAMP signaling assays, and receptor-selectivity profiling. Verve makes no health claims.
What is TB-500?
TB-500 is a synthetic 43-amino-acid peptide based on an active fragment of thymosin beta-4. Verve supplies it as a research compound for laboratory use only.
What is TB-500 studied for in research?
It is used in cell-migration, actin-regulation, angiogenesis, and tissue-repair research models. It is not for human or veterinary use.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.