MOTS-C vs Tesamorelin
MOTS-C and Tesamorelin are both studied in weight research, but they are different classes of compound with different reported research applications.
✓ both US-made · third-party tested · batch COA on every order
Last updated August 25, 2026
How do MOTS-C and Tesamorelin differ?
MOTS-C (Mitochondrial-derived 16-amino-acid peptide) is catalogued under weight & metabolic research; Tesamorelin (Synthetic GHRH analog · secretagogue research) is catalogued under weight & metabolic research. Verve lists 5 reported research applications for MOTS-C and 4 for Tesamorelin. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | MOTS-C | Tesamorelin |
|---|---|---|
| compound class | Mitochondrial-derived 16-amino-acid peptide | Synthetic GHRH analog · secretagogue research |
| research area | weight & metabolic | weight & metabolic |
| reported research applications | 5 listed | 4 listed |
| supplied as | single compound | single compound |
| catalog sizes | 10mg | 20mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | available | available |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $78.99 | $214.49 |
| availability | in stock | in stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is MOTS-C and what is Tesamorelin?
MOTS-C is classified as Mitochondrial-derived 16-amino-acid peptide; Tesamorelin as Synthetic GHRH analog · secretagogue research. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
MOTS-C
Mitochondrial-derived 16-amino-acid peptide
MOTS-c is a 16-amino-acid peptide encoded not by nuclear DNA but by a short open reading frame within the mitochondrial 12S rRNA gene. It belongs to the mitochondrial-derived peptide family, a group of small peptides that are of interest in research precisely because their genetic origin sits inside the organelle rather than the nucleus.
full MOTS-C profile →Tesamorelin
Synthetic GHRH analog · secretagogue research
Tesamorelin is a synthetic 44-amino-acid peptide, a stabilized analog of growth-hormone-releasing hormone (GHRH). Verve supplies it as a high-purity research compound for endocrine and secretagogue research.
full Tesamorelin profile →Which research models is each compound studied in?
MOTS-C and Tesamorelin both sit inside weight & metabolic research, so their listed models share framing while differing in specifics. The table lists 5 reported research applications for MOTS-C and 4 for Tesamorelin. Rows are per compound, not equivalences.
| MOTS-C — reported research applications | Tesamorelin — reported research applications |
|---|---|
| Mitochondrial-derived peptide and retrograde-signaling research | GHRH-receptor and secretagogue research |
| AMPK pathway research models | Endocrine-signaling research models |
| One-carbon (folate–methionine) metabolism studies | Peptide pharmacokinetics and stability research |
| Cellular energy-metabolism and substrate-utilization research | Metabolic research models |
| Exercise-physiology and metabolic-stress research models | — |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for MOTS-C and Tesamorelin?
MOTS-C is listed from $78.99 and Tesamorelin from $214.49. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| MOTS-C | 10mg | $78.99 | in stock |
| Tesamorelin | 20mg | $214.49 | in stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about MOTS-C and Tesamorelin
What is MOTS-C?
MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame in the mitochondrial genome. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is MOTS-C studied for in research?
It is used in mitochondrial-signaling research, including AMPK pathway activity, one-carbon metabolism, and retrograde signaling between mitochondria and the nucleus in in-vitro and pre-clinical models. Verve makes no health claims.
What is Tesamorelin?
Tesamorelin is a synthetic 44-amino-acid analog of growth-hormone-releasing hormone (GHRH). Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Tesamorelin studied for in research?
It is used as a GHRH-receptor agonist model in secretagogue and endocrine-signaling research. Verve makes no human- or veterinary-use claims.
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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.