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MOTS-C vs Selank

MOTS-C and Selank come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.

✓ both US-made · third-party tested · batch COA on every order

Last updated August 25, 2026

How do MOTS-C and Selank differ?

MOTS-C (Mitochondrial-derived 16-amino-acid peptide) is catalogued under weight & metabolic research; Selank (Synthetic heptapeptide) is catalogued under mind & sleep research. Verve lists 5 reported research applications for MOTS-C and 5 for Selank. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.

MOTS-C compared with Selank across compound class, research area, supply format, purity standard, documentation, catalog price and stock.
fieldMOTS-CSelank
compound classMitochondrial-derived 16-amino-acid peptideSynthetic heptapeptide
research areaweight & metabolicmind & sleep
reported research applications5 listed5 listed
supplied assingle compoundsingle compound
catalog sizes10mg10mg
purity standard99%+ by HPLC99%+ by HPLC
manufacturedUnited StatesUnited States
batch COApublished per lotpublished per lot
endotoxin-tested optionavailableavailable
co-formulated together innot co-formulatednot co-formulated
price from$78.99$64.99
availabilityin stockin stock

Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.

What is MOTS-C and what is Selank?

MOTS-C is classified as Mitochondrial-derived 16-amino-acid peptide; Selank as Synthetic heptapeptide. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.

MOTS-C

Mitochondrial-derived 16-amino-acid peptide

MOTS-c is a 16-amino-acid peptide encoded not by nuclear DNA but by a short open reading frame within the mitochondrial 12S rRNA gene. It belongs to the mitochondrial-derived peptide family, a group of small peptides that are of interest in research precisely because their genetic origin sits inside the organelle rather than the nucleus.

full MOTS-C profile →

Selank

Synthetic heptapeptide

Selank is a synthetic heptapeptide, a seven-amino-acid chain built from the endogenous immunomodulatory tetrapeptide tuftsin with a C-terminal Pro-Gly-Pro extension added to increase stability. Verve supplies it as a high-purity research compound for neuroscience and peptide-signaling research.

full Selank profile →

Which research models is each compound studied in?

MOTS-C sits in weight & metabolic research and Selank in mind & sleep research, so their listed models largely do not intersect. The table lists 5 reported research applications for MOTS-C and 5 for Selank. Rows are per compound, not equivalences.

Reported research applications listed for MOTS-C and for Selank. Entries are listed per compound; a shared row is not a claim that the two applications are equivalent.
MOTS-C — reported research applicationsSelank — reported research applications
Mitochondrial-derived peptide and retrograde-signaling researchRegulatory-neuropeptide signaling research
AMPK pathway research modelsGABAergic and monoaminergic pathway research models
One-carbon (folate–methionine) metabolism studiesNeurotrophic gene-expression studies
Cellular energy-metabolism and substrate-utilization researchTuftsin-analog structure–activity research
Exercise-physiology and metabolic-stress research modelsPeptide-stability and degradation-kinetics research

Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.

What sizes and prices does verve list for MOTS-C and Selank?

MOTS-C is listed from $78.99 and Selank from $64.99. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.

Catalog sizes, single-vial prices and stock status for MOTS-C and Selank.
compoundsize listedpriceavailability
MOTS-C10mg$78.99in stock
Selank10mg$64.99in stock

Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.

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Frequently asked questions about MOTS-C and Selank

What is MOTS-C?

MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame in the mitochondrial genome. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.

What is MOTS-C studied for in research?

It is used in mitochondrial-signaling research, including AMPK pathway activity, one-carbon metabolism, and retrograde signaling between mitochondria and the nucleus in in-vitro and pre-clinical models. Verve makes no health claims.

What is Selank?

Selank is a synthetic seven-amino-acid peptide derived from the tetrapeptide tuftsin with a stabilizing Pro-Gly-Pro extension. Verve supplies it as a research compound for laboratory use only.

What is Selank studied for in research?

It is used as a model neuropeptide in GABAergic and monoaminergic signaling research, neurotrophic gene-expression studies, and peptide-stability work. It is not for human or veterinary use.

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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.