Melanotan I vs PT-141
Melanotan I and PT-141 are both studied in skin research, but they are different classes of compound with different reported research applications.
✓ both US-made · third-party tested · batch COA on every order
Last updated August 25, 2026
How do Melanotan I and PT-141 differ?
Melanotan I (Synthetic linear tridecapeptide) is catalogued under skin & glow research; PT-141 (Synthetic cyclic heptapeptide melanocortin agonist) is catalogued under skin & glow research. Verve lists 5 reported research applications for Melanotan I and 5 for PT-141. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | Melanotan I | PT-141 |
|---|---|---|
| compound class | Synthetic linear tridecapeptide | Synthetic cyclic heptapeptide melanocortin agonist |
| research area | skin & glow | skin & glow |
| reported research applications | 5 listed | 5 listed |
| supplied as | single compound | single compound |
| catalog sizes | 10mg | 10mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | not offered | not offered |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $64.99 | $50.49 |
| availability | in stock | out of stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is Melanotan I and what is PT-141?
Melanotan I is classified as Synthetic linear tridecapeptide; PT-141 as Synthetic cyclic heptapeptide melanocortin agonist. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
Melanotan I
Synthetic linear tridecapeptide
Melanotan I, also known as afamelanotide, is a synthetic linear tridecapeptide and a structural analog of alpha-melanocyte-stimulating hormone (alpha-MSH), the endogenous ligand of the melanocortin receptor family. Substitutions to the native alpha-MSH sequence give the analog greater resistance to enzymatic degradation, which is why it is frequently selected as a stable reference ligand in melanocortin-pathway research.
full Melanotan I profile →PT-141
Synthetic cyclic heptapeptide melanocortin agonist
PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide analog of the melanocortin family, structurally related to alpha-melanocyte-stimulating hormone and to the earlier research analog Melanotan II. Verve supplies it as a high-purity research compound for laboratory melanocortin-receptor research.
full PT-141 profile →Which research models is each compound studied in?
Melanotan I and PT-141 both sit inside skin & glow research, so their listed models share framing while differing in specifics. The table lists 5 reported research applications for Melanotan I and 5 for PT-141. Rows are per compound, not equivalences.
| Melanotan I — reported research applications | PT-141 — reported research applications |
|---|---|
| Melanocortin-1 receptor (MC1R) binding and selectivity research | Melanocortin-receptor (MC1R/MC3R/MC4R) binding research |
| Melanogenesis research in cultured melanocyte models | cAMP and G-protein-coupled receptor signaling assays |
| cAMP second-messenger signaling research | Receptor-selectivity and structure–activity profiling |
| Comparative alpha-MSH analog and receptor-agonist studies | MC1R and melanogenesis research models in cell culture |
| Peptide-stability and enzymatic-degradation research | Cyclic-peptide stability and conformation research |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for Melanotan I and PT-141?
Melanotan I is listed from $64.99 and PT-141 from $50.49. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| Melanotan I | 10mg | $64.99 | in stock |
| PT-141 | 10mg | $50.49 | out of stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about Melanotan I and PT-141
What is Melanotan I?
Melanotan I (afamelanotide) is a synthetic tridecapeptide analog of alpha-melanocyte-stimulating hormone. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Melanotan I studied for in research?
It is used as a reference MC1R agonist in melanocortin receptor-binding, cAMP signaling, and melanogenesis research models in cultured cells. Verve makes no claims about use in humans or animals.
What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide melanocortin analog structurally related to alpha-MSH. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is PT-141 studied for in research?
It is used as a reference agonist in melanocortin-receptor research, including MC1R, MC3R, and MC4R binding studies, cAMP signaling assays, and receptor-selectivity profiling. Verve makes no health claims.
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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.