GLP-3 RTA vs PT-141
GLP-3 RTA and PT-141 come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.
✓ both US-made · third-party tested · batch COA on every order
Last updated August 25, 2026
How do GLP-3 RTA and PT-141 differ?
GLP-3 RTA (Synthetic triple-agonist peptide) is catalogued under weight & metabolic research; PT-141 (Synthetic cyclic heptapeptide melanocortin agonist) is catalogued under skin & glow research. Verve lists 5 reported research applications for GLP-3 RTA and 5 for PT-141. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | GLP-3 RTA | PT-141 |
|---|---|---|
| compound class | Synthetic triple-agonist peptide | Synthetic cyclic heptapeptide melanocortin agonist |
| research area | weight & metabolic | skin & glow |
| reported research applications | 5 listed | 5 listed |
| supplied as | single compound | single compound |
| catalog sizes | 10mg · 20mg · 30mg | 10mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | available | not offered |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $142.99 | $50.49 |
| availability | in stock | out of stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is GLP-3 RTA and what is PT-141?
GLP-3 RTA is classified as Synthetic triple-agonist peptide; PT-141 as Synthetic cyclic heptapeptide melanocortin agonist. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
GLP-3 RTA
Synthetic triple-agonist peptide
GLP-3 RTA is a synthetic single-chain peptide engineered to act at three related class B G-protein-coupled receptors at once: the GLP-1 receptor, the GIP receptor, and the glucagon receptor. Its backbone is derived from the incretin peptide family and carries a fatty-acid modification that extends plasma half-life in pre-clinical systems, making it a widely cited reference agonist in incretin-receptor research.
full GLP-3 RTA profile →PT-141
Synthetic cyclic heptapeptide melanocortin agonist
PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide analog of the melanocortin family, structurally related to alpha-melanocyte-stimulating hormone and to the earlier research analog Melanotan II. Verve supplies it as a high-purity research compound for laboratory melanocortin-receptor research.
full PT-141 profile →Which research models is each compound studied in?
GLP-3 RTA sits in weight & metabolic research and PT-141 in skin & glow research, so their listed models largely do not intersect. The table lists 5 reported research applications for GLP-3 RTA and 5 for PT-141. Rows are per compound, not equivalences.
| GLP-3 RTA — reported research applications | PT-141 — reported research applications |
|---|---|
| GLP-1, GIP, and glucagon receptor agonism research | Melanocortin-receptor (MC1R/MC3R/MC4R) binding research |
| cAMP and class B GPCR signaling research models | cAMP and G-protein-coupled receptor signaling assays |
| Comparative single-, dual-, and triple-agonist pharmacology studies | Receptor-selectivity and structure–activity profiling |
| Metabolic-pathway and nutrient-handling research models | MC1R and melanogenesis research models in cell culture |
| Peptide half-life, lipidation, and stability research | Cyclic-peptide stability and conformation research |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for GLP-3 RTA and PT-141?
GLP-3 RTA is listed from $142.99 and PT-141 from $50.49. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| GLP-3 RTA | 10mg | $142.99 | in stock |
| GLP-3 RTA | 20mg | $242.99 | in stock |
| GLP-3 RTA | 30mg | $328.99 | in stock |
| PT-141 | 10mg | $50.49 | out of stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about GLP-3 RTA and PT-141
What is GLP-3 RTA?
GLP-3 RTA is a synthetic peptide that acts as an agonist at three receptors — GLP-1, GIP, and glucagon. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is GLP-3 RTA studied for in research?
In in-vitro and pre-clinical models it is used as a reference agonist in incretin-receptor pharmacology, cAMP signaling, and metabolic-pathway research. Verve makes no claims about use in humans or animals.
What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide melanocortin analog structurally related to alpha-MSH. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is PT-141 studied for in research?
It is used as a reference agonist in melanocortin-receptor research, including MC1R, MC3R, and MC4R binding studies, cAMP signaling assays, and receptor-selectivity profiling. Verve makes no health claims.
related comparisons
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.