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KLOW vs MOTS-C

KLOW and MOTS-C come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.

✓ both US-made · third-party tested · batch COA on every order

Last updated August 25, 2026

How do KLOW and MOTS-C differ?

KLOW (Four-peptide research blend · cellular research) is catalogued under recovery & gut research; MOTS-C (Mitochondrial-derived 16-amino-acid peptide) is catalogued under weight & metabolic research. Verve lists 4 reported research applications for KLOW and 5 for MOTS-C. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.

KLOW compared with MOTS-C across compound class, research area, supply format, purity standard, documentation, catalog price and stock.
fieldKLOWMOTS-C
compound classFour-peptide research blend · cellular researchMitochondrial-derived 16-amino-acid peptide
research arearecovery & gutweight & metabolic
reported research applications4 listed5 listed
supplied asco-formulated blendsingle compound
catalog sizes80mg · 160mg10mg
purity standard99%+ by HPLC99%+ by HPLC
manufacturedUnited StatesUnited States
batch COApublished per lotpublished per lot
endotoxin-tested optionavailableavailable
co-formulated together innot co-formulatednot co-formulated
price from$185.99$78.99
availabilityin stockin stock

Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.

What is KLOW and what is MOTS-C?

KLOW is classified as Four-peptide research blend · cellular research; MOTS-C as Mitochondrial-derived 16-amino-acid peptide. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.

KLOW

Four-peptide research blend · cellular research

KLOW is a research blend that combines four of the most-studied peptides (BPC-157, TB-500, GHK-Cu, and KPV) in a single vial. Verve supplies it as a high-purity, batch-tested research preparation for cellular research.

full KLOW profile →

MOTS-C

Mitochondrial-derived 16-amino-acid peptide

MOTS-c is a 16-amino-acid peptide encoded not by nuclear DNA but by a short open reading frame within the mitochondrial 12S rRNA gene. It belongs to the mitochondrial-derived peptide family, a group of small peptides that are of interest in research precisely because their genetic origin sits inside the organelle rather than the nucleus.

full MOTS-C profile →

Which research models is each compound studied in?

KLOW sits in recovery & gut research and MOTS-C in weight & metabolic research, so their listed models largely do not intersect. The table lists 4 reported research applications for KLOW and 5 for MOTS-C. Rows are per compound, not equivalences.

Reported research applications listed for KLOW and for MOTS-C. Entries are listed per compound; a shared row is not a claim that the two applications are equivalent.
KLOW — reported research applicationsMOTS-C — reported research applications
Multi-compound cellular researchMitochondrial-derived peptide and retrograde-signaling research
Tissue-repair research modelsAMPK pathway research models
Extracellular-matrix and remodeling researchOne-carbon (folate–methionine) metabolism studies
Comparative peptide researchCellular energy-metabolism and substrate-utilization research
Exercise-physiology and metabolic-stress research models

Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.

What sizes and prices does verve list for KLOW and MOTS-C?

KLOW is listed from $185.99 and MOTS-C from $78.99. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.

Catalog sizes, single-vial prices and stock status for KLOW and MOTS-C.
compoundsize listedpriceavailability
KLOW80mg$185.99in stock
KLOW160mg$314.49in stock
MOTS-C10mg$78.99in stock

Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.

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Frequently asked questions about KLOW and MOTS-C

What is KLOW?

KLOW is a research blend of four peptides (BPC-157, TB-500, GHK-Cu, and KPV) in one vial. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.

What is KLOW studied for in research?

It is used in multi-compound cellular and tissue-repair research models where these four peptides are studied together. Verve makes no health claims.

What is MOTS-C?

MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame in the mitochondrial genome. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.

What is MOTS-C studied for in research?

It is used in mitochondrial-signaling research, including AMPK pathway activity, one-carbon metabolism, and retrograde signaling between mitochondria and the nucleus in in-vitro and pre-clinical models. Verve makes no health claims.

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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.