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acetyl octapeptide-3 · snare-complex research

SNAP-8 Research Peptide, US-Made & Third-Party Tested

✓ US-made · third-party tested · free US shipping over $100

last updated · reviewed by the verve research team

what is snap-8?

SNAP-8 is a synthetic acetylated octapeptide, an elongated analog of acetyl hexapeptide-3 (Argireline), based on a sequence from the SNAP-25 protein. Verve supplies it as a research compound for laboratory use only. It is catalogued under skin & glow as a synthetic acetylated octapeptide.

SNAP-8 is a synthetic acetylated octapeptide, an elongated analog of acetyl hexapeptide-3 (Argireline) extended by two additional residues. Its sequence is modeled on the N-terminal region of SNAP-25, one of the proteins that assembles the SNARE complex, which makes it a convenient synthetic tool for studying that assembly in vitro.

In the laboratory, SNAP-8 is investigated in SNARE-complex and neurotransmitter-vesicle research, where it is used as a competitive peptide model for examining how SNAP-25 participates in vesicle docking and fusion, and as a reference compound in dermal cell-culture and peptide-permeation studies. Verve manufactures SNAP-8 in the United States, tests every batch by HPLC to a 99%+ purity standard, and publishes a batch-level certificate of analysis.

snap-8 specifications

Reference data for SNAP-8 as supplied by verve for laboratory research use only.

SNAP-8 research compound specifications
CompoundSNAP-8
Compound classSynthetic acetylated octapeptide
Research areaskin & glow
Primary research focusSNARE-complex research
Purity standard99%+ purity standard, HPLC-verified per batch
Supplied asSingle research compound
Endotoxin-tested optionNot offered
Catalog sizes10mg
Catalog pricefrom $50
AvailabilityOut of stock
Intended useIn-vitro laboratory research use only. Not for human or veterinary use.
Reference last reviewed

what is snap-8 used for in research?

SNAP-8 is supplied strictly for laboratory research use only. Reported research contexts include:

  • SNARE-complex assembly research
  • Neurotransmitter-vesicle docking and fusion research models
  • SNAP-25 competitive-peptide studies
  • Dermal cell-culture and fibroblast research models
  • Comparative octapeptide and hexapeptide analog research

how pure is snap-8?

purity, third-party testing & the certificate of analysis

Every batch of verve SNAP-8is synthesized and vial-filled in the United States and screened by an independent, accredited laboratory. Chromatographic purity and quantity are measured by HPLC-UV/VIS; where the panel includes them, endotoxin is screened by LAL and sterility by USP <71>, with the sterility result reported as no growth detected or as pending while the culture is still running. Products are manufactured to a 99%+ purity standard where stated.

Published certificates for the lots currently in our COA library cover part of the range; a published report for this compound is not in the library yet. Orders placed Monday–Friday ship by 2pm CT, free over $100, with damage protection in transit and full US tracking.

SNAP-8, explained in 60 secondsthe plain-english version — what it is, where it shows up, and the lab report behind the vial

snap-8 frequently asked questions

What is SNAP-8?

SNAP-8 is a synthetic acetylated octapeptide, an elongated analog of acetyl hexapeptide-3 (Argireline), based on a sequence from the SNAP-25 protein. Verve supplies it as a research compound for laboratory use only.

What is SNAP-8 studied for in research?

It is used as a peptide model in SNARE-complex and neurotransmitter-vesicle research, and as a reference compound in dermal cell-culture studies. It is not for human or veterinary use.

How pure is Verve's SNAP-8?

It is US-made, verified to a 99%+ purity standard by HPLC, and third-party tested, with a batch COA included on every order.

Is a COA included?

Yes, a downloadable certificate of analysis ships with every order and is matched to your vial's batch code.

snap-8 research references

  1. Kluczyk A, Ludwiczak J, Modzel M, Kuczer M, Cebrat M, Biernat M, et al. Argireline: Needle-Free Botox as Analytical Challenge. Chem Biodivers. 2021;18(3):e2000992.Analytical-chemistry study addressing detection, identification and quantification of acetylated SNAP-25-derived peptides in complex matrices.
  2. Blanes-Mira C, Merino JM, Valera E, Fernández-Ballester G, Gutiérrez LM, Viniegra S, et al. Small peptides patterned after the N-terminus domain of SNAP25 inhibit SNARE complex assembly and regulated exocytosis. J Neurochem. 2004;88(1):124-35.In-vitro study of short peptides modelled on the SNAP-25 N-terminal domain, measuring their effect on SNARE complex assembly and regulated exocytosis. This is the peptide class SNAP-8 belongs to, not a study of SNAP-8 itself.

research areas snap-8 appears in

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US-made, third-party tested research peptides, every vial batch-traceable, every COA one click away.

verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.