Semax Research Peptide, US-Made & Third-Party Tested
✓ US-made · third-party tested · free US shipping over $100
last updated · reviewed by the verve research team
what is semax?
Semax is a synthetic seven-amino-acid peptide derived from a fragment of ACTH. Verve supplies it as a research compound for laboratory use only. It is catalogued under mind & sleep as a synthetic heptapeptide. Every batch is US-made, third-party tested, and shipped with batch-level documentation.
Semax is a synthetic heptapeptide, a seven-amino-acid chain based on a fragment of adrenocorticotropic hormone, ACTH(4–10), with a C-terminal Pro-Gly-Pro extension added for stability. Verve supplies it as a high-purity research compound for neuroscience research.
Semax is studied in neuroscience research as a model neuropeptide, including work on neurotrophic signaling (such as BDNF expression) and neuroprotection in cellular and pre-clinical models. Verve's Semax is manufactured in the US, third-party tested, and shipped with a batch-level COA.
semax specifications
Reference data for Semax as supplied by verve for laboratory research use only.
| Compound | Semax |
|---|---|
| Compound class | Synthetic heptapeptide |
| Research area | mind & sleep |
| Primary research focus | neuro research |
| Purity standard | 99%+ purity standard, HPLC-verified per batch |
| Supplied as | Single research compound |
| Endotoxin-tested option | Available |
| Catalog sizes | 10mg |
| Catalog price | from $65 |
| Availability | In stock |
| Intended use | In-vitro laboratory research use only. Not for human or veterinary use. |
| Reference last reviewed |
what is semax used for in research?
Semax is supplied strictly for laboratory research use only. Reported research contexts include:
- Neurotrophic-signaling (BDNF) research
- Neuroprotection research models
- Cognitive-research models
- Peptide-stability research
how pure is semax?
purity, third-party testing & the certificate of analysis
Every batch of verve Semaxis synthesized and vial-filled in the United States and screened by an independent, accredited laboratory. Chromatographic purity and quantity are measured by HPLC-UV/VIS; where the panel includes them, endotoxin is screened by LAL and sterility by USP <71>, with the sterility result reported as no growth detected or as pending while the culture is still running. Products are manufactured to a 99%+ purity standard where stated.
That lab report is the certificate of analysis. Match the batch code printed on your vial to the row in our COA library and you're reading the exact report for the exact vial in your hand. This compound's current report covers lot 3548321, published 2026-05-27. Orders placed Monday–Friday ship by 2pm CT, free over $100, with damage protection in transit and full US tracking.
Semax, explained in 60 secondsthe plain-english version — what it is, where it shows up, and the lab report behind the vialwhere to buy semax for research
Semax Nasal Spraymind & sleepfrom $65browse all mind & sleep →semax frequently asked questions
What is Semax?
Semax is a synthetic seven-amino-acid peptide derived from a fragment of ACTH. Verve supplies it as a research compound for laboratory use only.
What is Semax studied for in research?
It is used as a model neuropeptide in neurotrophic-signaling, neuroprotection, and cognitive research. It is not for human or veterinary use.
How pure is Verve's Semax?
It is US-made, prepared to a 99%+ purity standard, and third-party tested, with a batch COA included.
Is a COA included?
Yes, every order ships with a downloadable batch-level certificate of analysis.
semax research references
- Medvedeva EV, Dmitrieva VG, Povarova OV, Limborska SA, Skvortsova VI, Myasoedov NF, et al. The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis. BMC Genomics. 2014;15:228.Performed genome-wide transcriptional profiling of rat brain tissue in a focal cerebral ischemia model.
- Shadrina M, Kolomin T, Agapova T, Agniullin Y, Shram S, Slominsky P, et al. Comparison of the temporary dynamics of NGF and BDNF gene expression in rat hippocampus, frontal cortex, and retina under Semax action. J Mol Neurosci. 2010;41(1):30-5.Tracked the time course of NGF and BDNF transcript levels in three rat neural tissues.
- Agapova TY, Agniullin YV, Shadrina MI, Shram SI, Slominsky PA, Lymborska SA, et al. Neurotrophin gene expression in rat brain under the action of Semax, an analogue of ACTH 4-10. Neurosci Lett. 2007;417(2):201-5.Profiled BDNF and NGF gene expression across rat brain regions in a rodent model.
- Dolotov OV, Karpenko EA, Inozemtseva LS, Seredenina TS, Levitskaya NG, Rozyczka J, et al. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Res. 2006;1117(1):54-60.Measured BDNF and trkB transcript and protein levels in rat hippocampus following Semax exposure.
- Potaman VN, Alfeeva LY, Kamensky AA, Nezavibatko VN. Degradation of ACTH/MSH(4-10) and its synthetic analog semax by rat serum enzymes: an inhibitor study. Peptides. 1993;14(3):491-5.Characterised enzymatic degradation kinetics of Semax versus the parent ACTH(4-10) fragment in rat serum in vitro.
research areas semax appears in
semax vs other research compounds
all comparisons →research compounds related to semax
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US-made, third-party tested research peptides, every vial batch-traceable, every COA one click away.
verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.