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delta sleep-inducing peptide · neuromodulation research

DSIP Research Peptide, US-Made & Third-Party Tested

✓ US-made · third-party tested · free US shipping over $100

last updated · reviewed by the verve research team

what is dsip?

DSIP is a synthetic nine-amino-acid peptide (a nonapeptide) known as delta sleep-inducing peptide, a name that reflects the waveform observed in the animal model where it was first characterized. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.

DSIP (delta sleep-inducing peptide) is a synthetic nonapeptide, a nine-amino-acid sequence first isolated during neuropeptide fractionation studies and named for the electroencephalographic waveform observed in the animal model where it was characterized. Verve supplies it as a high-purity research compound for laboratory neuromodulation research.

In research use, DSIP serves as a reference nonapeptide in studies of neuromodulatory signaling, blood-brain-barrier peptide transport, and neuroendocrine pathway regulation in cellular and pre-clinical models. Verve's DSIP is manufactured in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a published batch-level certificate of analysis.

dsip specifications

Reference data for DSIP as supplied by verve for laboratory research use only.

DSIP research compound specifications
CompoundDSIP
Compound classSynthetic nonapeptide
Research areamind & sleep
Primary research focusneuromodulation research
Purity standard99%+ purity standard, HPLC-verified per batch
Supplied asSingle research compound
Endotoxin-tested optionNot offered
Catalog sizes10mg
Catalog pricefrom $65
AvailabilityOut of stock
Intended useIn-vitro laboratory research use only. Not for human or veterinary use.
Reference last reviewed

what is dsip used for in research?

DSIP is supplied strictly for laboratory research use only. Reported research contexts include:

  • Neuromodulatory peptide-signaling research
  • Neuroendocrine pathway research models
  • Blood-brain-barrier peptide-transport studies
  • Circadian and electrophysiology research models
  • Nonapeptide stability and degradation research

how pure is dsip?

purity, third-party testing & the certificate of analysis

Every batch of verve DSIPis synthesized and vial-filled in the United States and screened by an independent, accredited laboratory. Chromatographic purity and quantity are measured by HPLC-UV/VIS; where the panel includes them, endotoxin is screened by LAL and sterility by USP <71>, with the sterility result reported as no growth detected or as pending while the culture is still running. Products are manufactured to a 99%+ purity standard where stated.

Published certificates for the lots currently in our COA library cover part of the range; a published report for this compound is not in the library yet. Orders placed Monday–Friday ship by 2pm CT, free over $100, with damage protection in transit and full US tracking.

DSIP, explained in 60 secondsthe plain-english version — what it is, where it shows up, and the lab report behind the vial

dsip frequently asked questions

What is DSIP?

DSIP is a synthetic nine-amino-acid peptide (a nonapeptide) known as delta sleep-inducing peptide, a name that reflects the waveform observed in the animal model where it was first characterized. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.

What is DSIP studied for in research?

It is used as a reference nonapeptide in neuromodulation, neuroendocrine-signaling, and peptide-transport research models. Verve makes no claims about use in humans or animals.

How pure is Verve's DSIP?

It is US-made, verified to a 99%+ purity standard by HPLC, and third-party tested, with a batch COA on every order.

Is a COA included?

Yes, a downloadable batch-level certificate of analysis ships with every order, matched to your vial's batch code.

dsip research references

  1. Tukhovskaya EA, Ismailova AM, Shaykhutdinova ER, Slashcheva GA, Prudchenko IA, Mikhaleva II, et al. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules. 2021;26(17).Rodent study measuring motor-function scores in Sprague-Dawley rats following experimentally induced focal stroke.
  2. Roy K, Chauhan G, Kumari P, Wadhwa M, Alam S, Ray K, et al. Phosphorylated delta sleep inducing peptide restores spatial memory and p-CREB expression by improving sleep architecture at high altitude. Life Sci. 2018;209:282-290.Rat model study measuring sleep architecture, spatial-memory performance and hippocampal p-CREB expression under simulated high-altitude hypoxia.
  3. Kovalzon VM, Strekalova TV. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. J Neurochem. 2006;97(2):303-9.Critical review examining the strength of the evidence base for DSIP as a sleep factor, noting no DSIP gene, precursor protein or receptor has been identified.
  4. Graf MV, Kastin AJ. Delta-sleep-inducing peptide (DSIP): an update. Peptides. 1986;7(6):1165-87.Follow-up review summarising immunohistochemical and radioimmunochemical distribution data, noting the proposed adrenergic-modulation mechanism remained unestablished.
  5. Graf MV, Kastin AJ. Delta-sleep-inducing peptide (DSIP): a review. Neurosci Biobehav Rev. 1984;8(1):83-93.Review collating the early animal and in-vitro literature on DSIP, covering isolation, tissue distribution, and reported electrophysiological and neuroendocrine observations in those models.

research areas dsip appears in

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US-made, third-party tested research peptides, every vial batch-traceable, every COA one click away.

verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.