PT-141 vs Semax
PT-141 and Semax come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.
✓ both US-made · third-party tested · batch COA on every order
Last updated August 25, 2026
How do PT-141 and Semax differ?
PT-141 (Synthetic cyclic heptapeptide melanocortin agonist) is catalogued under skin & glow research; Semax (Synthetic heptapeptide · neuro research) is catalogued under mind & sleep research. Verve lists 5 reported research applications for PT-141 and 4 for Semax. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | PT-141 | Semax |
|---|---|---|
| compound class | Synthetic cyclic heptapeptide melanocortin agonist | Synthetic heptapeptide · neuro research |
| research area | skin & glow | mind & sleep |
| reported research applications | 5 listed | 4 listed |
| supplied as | single compound | single compound |
| catalog sizes | 10mg | 10mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | not offered | available |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $50.49 | $64.99 |
| availability | out of stock | in stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is PT-141 and what is Semax?
PT-141 is classified as Synthetic cyclic heptapeptide melanocortin agonist; Semax as Synthetic heptapeptide · neuro research. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
PT-141
Synthetic cyclic heptapeptide melanocortin agonist
PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide analog of the melanocortin family, structurally related to alpha-melanocyte-stimulating hormone and to the earlier research analog Melanotan II. Verve supplies it as a high-purity research compound for laboratory melanocortin-receptor research.
full PT-141 profile →Semax
Synthetic heptapeptide · neuro research
Semax is a synthetic heptapeptide, a seven-amino-acid chain based on a fragment of adrenocorticotropic hormone, ACTH(4–10), with a C-terminal Pro-Gly-Pro extension added for stability. Verve supplies it as a high-purity research compound for neuroscience research.
full Semax profile →Which research models is each compound studied in?
PT-141 sits in skin & glow research and Semax in mind & sleep research, so their listed models largely do not intersect. The table lists 5 reported research applications for PT-141 and 4 for Semax. Rows are per compound, not equivalences.
| PT-141 — reported research applications | Semax — reported research applications |
|---|---|
| Melanocortin-receptor (MC1R/MC3R/MC4R) binding research | Neurotrophic-signaling (BDNF) research |
| cAMP and G-protein-coupled receptor signaling assays | Neuroprotection research models |
| Receptor-selectivity and structure–activity profiling | Cognitive-research models |
| MC1R and melanogenesis research models in cell culture | Peptide-stability research |
| Cyclic-peptide stability and conformation research | — |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for PT-141 and Semax?
PT-141 is listed from $50.49 and Semax from $64.99. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| PT-141 | 10mg | $50.49 | out of stock |
| Semax | 10mg | $64.99 | in stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about PT-141 and Semax
What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide melanocortin analog structurally related to alpha-MSH. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is PT-141 studied for in research?
It is used as a reference agonist in melanocortin-receptor research, including MC1R, MC3R, and MC4R binding studies, cAMP signaling assays, and receptor-selectivity profiling. Verve makes no health claims.
What is Semax?
Semax is a synthetic seven-amino-acid peptide derived from a fragment of ACTH. Verve supplies it as a research compound for laboratory use only.
What is Semax studied for in research?
It is used as a model neuropeptide in neurotrophic-signaling, neuroprotection, and cognitive research. It is not for human or veterinary use.
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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.