Ipamorelin vs PT-141
Ipamorelin and PT-141 come from different research areas and are studied in largely separate models — researchers usually compare them when scoping a broader protocol.
✓ both US-made · third-party tested · batch COA on every order
Last updated August 25, 2026
How do Ipamorelin and PT-141 differ?
Ipamorelin (Synthetic pentapeptide secretagogue) is catalogued under longevity & cellular research; PT-141 (Synthetic cyclic heptapeptide melanocortin agonist) is catalogued under skin & glow research. Verve lists 5 reported research applications for Ipamorelin and 5 for PT-141. Both are made in the United States, screened by HPLC to a 99%+ purity standard, and shipped with a batch-level certificate of analysis.
| field | Ipamorelin | PT-141 |
|---|---|---|
| compound class | Synthetic pentapeptide secretagogue | Synthetic cyclic heptapeptide melanocortin agonist |
| research area | longevity & cellular | skin & glow |
| reported research applications | 5 listed | 5 listed |
| supplied as | single compound | single compound |
| catalog sizes | 5mg · 10mg | 10mg |
| purity standard | 99%+ by HPLC | 99%+ by HPLC |
| manufactured | United States | United States |
| batch COA | published per lot | published per lot |
| endotoxin-tested option | available | not offered |
| co-formulated together in | not co-formulated | not co-formulated |
| price from | $64.99 | $50.49 |
| availability | out of stock | out of stock |
Prices and stock read live from the catalog. Both compounds are supplied strictly as reference materials for in-vitro laboratory research.
What is Ipamorelin and what is PT-141?
Ipamorelin is classified as Synthetic pentapeptide secretagogue; PT-141 as Synthetic cyclic heptapeptide melanocortin agonist. Both profiles below cover scientific identity only — what the molecule is and which laboratory models it appears in. Verve supplies both strictly as in-vitro reference materials, and neither profile describes human or veterinary use.
Ipamorelin
Synthetic pentapeptide secretagogue
Ipamorelin is a synthetic pentapeptide and a selective growth-hormone secretagogue, meaning it is characterized in the literature as an agonist at the growth-hormone secretagogue receptor (GHS-R1a), the same receptor targeted by the endogenous ligand ghrelin. Its selectivity profile is the reason it is so frequently chosen as a reference agonist in receptor-signaling work.
full Ipamorelin profile →PT-141
Synthetic cyclic heptapeptide melanocortin agonist
PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide analog of the melanocortin family, structurally related to alpha-melanocyte-stimulating hormone and to the earlier research analog Melanotan II. Verve supplies it as a high-purity research compound for laboratory melanocortin-receptor research.
full PT-141 profile →Which research models is each compound studied in?
Ipamorelin sits in longevity & cellular research and PT-141 in skin & glow research, so their listed models largely do not intersect. The table lists 5 reported research applications for Ipamorelin and 5 for PT-141. Rows are per compound, not equivalences.
| Ipamorelin — reported research applications | PT-141 — reported research applications |
|---|---|
| GHS-R1a (ghrelin receptor) binding and agonist research | Melanocortin-receptor (MC1R/MC3R/MC4R) binding research |
| Secretagogue-pathway signal-transduction research | cAMP and G-protein-coupled receptor signaling assays |
| Comparative receptor-selectivity studies against non-selective secretagogues | Receptor-selectivity and structure–activity profiling |
| Endocrine-signaling research models | MC1R and melanogenesis research models in cell culture |
| Peptide stability and structure–activity research | Cyclic-peptide stability and conformation research |
Research contexts only. Both compounds are supplied for laboratory research use only, and no entry above describes an effect in humans or animals.
What sizes and prices does verve list for Ipamorelin and PT-141?
Ipamorelin is listed from $64.99 and PT-141 from $50.49. The table below is every catalog size verve currently lists for the two compounds, at single-vial prices before the automatic multi-compound discount. Sizes describe the vial format supplied to the laboratory, nothing more.
| compound | size listed | price | availability |
|---|---|---|---|
| Ipamorelin | 5mg | $64.99 | out of stock |
| Ipamorelin | 10mg | $114.49 | out of stock |
| PT-141 | 10mg | $50.49 | out of stock |
Any 2 different compounds take 20% off, any 3 take 30% — applied automatically in the cart, no code. Orders placed Monday–Friday ship by 2pm CT, free over $100.
shop the compounds →Frequently asked questions about Ipamorelin and PT-141
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide characterized as a selective agonist at the growth-hormone secretagogue receptor (GHS-R1a). Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is Ipamorelin studied for in research?
It is used as a reference agonist in GHS-R1a receptor-binding and secretagogue-pathway signaling research in in-vitro and pre-clinical models. Verve makes no claims about effects in humans or animals.
What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide melanocortin analog structurally related to alpha-MSH. Verve supplies it as a research compound for laboratory use only, not for human or veterinary use.
What is PT-141 studied for in research?
It is used as a reference agonist in melanocortin-receptor research, including MC1R, MC3R, and MC4R binding studies, cAMP signaling assays, and receptor-selectivity profiling. Verve makes no health claims.
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verve products are sold for laboratory research and development purposes only and are not intended for human or veterinary use of any kind. statements on this site have not been evaluated by the FDA.